Colorectal Pancreatic Metastases: A Three-Case Series and Literature Review
Emil Matei, Silviu Ciurea, Vlad Herlea, Bogdan Mihail Dorobantu, Catalin VasilescuBrief Report, no. 1, 2025
Article DOI: 10.21614/chirurgia.3083
Introduction: Pancreatic metastases are very rare tumors comprising 2-5 % of all malignant tumors of the pancreas. Colorectal pancreatic metastases are rare - 1.7%.
Clinical features: Three patients with colo-rectal pancreatic metastasis were resected in our departament. The immunohsitochemical examination was positive for colorectal origin. Extensive imagistic work-up excluded extrapancreatic disease and allowed the surgical resection.
Results: Three patients with personal history of colorectal cancer (2 - colon, 1 -rectal) were diagnosed with isolated pancreatic metastasis (2 in the head and one in body). Standard pancreatic resections were performed (2 pancreatico-duodenectomies and one distal spleno-pancreatectomy). One patient with associated vascular resection died postoperatively. The other two developed extrapancreatic recurrence and only one was resected (alive and disease free); the other died under systemic therapy.
Conclusions: Surgical resection is recommended in selected patients, surgically fit, with resectable oligometastatic disease, in high-volume center with experience in pancreatic surgery.
Clinical features: Three patients with colo-rectal pancreatic metastasis were resected in our departament. The immunohsitochemical examination was positive for colorectal origin. Extensive imagistic work-up excluded extrapancreatic disease and allowed the surgical resection.
Results: Three patients with personal history of colorectal cancer (2 - colon, 1 -rectal) were diagnosed with isolated pancreatic metastasis (2 in the head and one in body). Standard pancreatic resections were performed (2 pancreatico-duodenectomies and one distal spleno-pancreatectomy). One patient with associated vascular resection died postoperatively. The other two developed extrapancreatic recurrence and only one was resected (alive and disease free); the other died under systemic therapy.
Conclusions: Surgical resection is recommended in selected patients, surgically fit, with resectable oligometastatic disease, in high-volume center with experience in pancreatic surgery.
Keywords: colorectal cancer, pancreatic metastasis, immunohistochemistry, pancreatic resection
